I use ObjectEdit allot. For making websites to gadget scripting. I have played around with it allot to tweak it to fit my own preference. I've found that using a white on warm black with subtle colours is easier on my eyes. And of course using a shorter tab indent, like 4 spaces. And I have also rewritten quite a few of the syntax files as well to they include more keywords. And I've had to write syntax files for some languages that didn't come by default with OE.
I was wondering what your setup is?
Should we have a OE syntax gallery at WC?
I have uploaded my current set of syntax files for anyone interested.